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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

All told, Ujiri parted with Terrence Ross, Jared Sullinger, and a total of three picks to acquire the two veterans.
[i'mju:niti]

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

“If they, say, delay a customary process for Korean imports and take other retaliatory measures on Korean products, there is nothing Korea can do about it,” he said.
"Hard to believe so many doctors lied in the papers. Can patients still trust them to help us treat diseases?" wrote one Sina Weibo user.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

While the FT online and full-time MBAs are not strictly comparable because the criteria used to judge them are slightly different, it is interesting to note that IE and Warwick Business School are among six schools to feature in both rankings.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

西尔万·埃索(Sylvan Esso),《咖啡》(Coffee), Partisan

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 社区精细化服务需加强
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

n. 紧张,压力
That was a less marked jump than the 3 percentage point rise from August to September, however, suggesting recent curbs to property purchases may be having some effect.
公司的运营情况不好。
[spu:n]

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

'东方之星'船体完全扶正
荷兰合作银行认为,外汇市场波动性也可能会成为影响未来12个月大宗农产品价格的因素,法国、荷兰和德国大选可能会导致欧元贬值。
In contrast, the nation witnessed a tumbling trend for minivans, whose volume totaled 71,300 units, a 31 percent drop year-on-year.
previous

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Fans of Twilight will finally get to see how the wedding, honeymoon, and birth scenes play out with the release of Breaking Dawn Part 1. But before you catch R

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Courtney Weaver

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

但事实上,作为一项新技术以及新运动,比特币在2014年表现出了猛烈的势头,而且在新的一年有望征服更多怀疑论者。诸多领域的指标证明了这一点:与比特币相关的初创企业和就业岗位数量大增;接受比特币的机构数量也大大增加;开发人员间的活动也较此前增强。
1.Actuary

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Better still was Iain Roberts, global managing director of the design company Ideo, who asked a question to which I hope never to hear the answer: “How to activate insights around latent mobility or multimodal needs?”
2. Get a Belstaff coat and blue scarf. The coat cost about 1350 pounds. It's got good twirl for those dramatic moments in life.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

达洛伊西奥解释道,自然语言处理有统计学和语义学两种方法,语义学系统试图解析文章的真实含义并对其进行简洁的译介。而统计学系统──设计Summly所采用的方法──无需这一过程;该系统保留词汇和句子的完整性,并通过运算从全文挑选出最具概括力的内容。它将每个句子或词汇进行分类、排序,以便挑出编入摘要的内容。这一过程极依赖数学计算,考量的是频率和分布,而非词语的含义。
还是得作秀

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

200911/88512.shtmlDuring NATO’s 1999 air war over Yugoslavia the Atlantic alliance struck hundreds of targets over Serbia and Kosovo. Most were uncontroversial: air-defense sites army headquarters and other military targets. The destruction of one target in particular however set off a wave of anti-Western—and anti-American in particular—protests half a world away. That target was the Chinese embassy in Belgrade.
马拉比这部长达800页的作品今年10月由布鲁姆斯伯里出版社(Bloomsbury)和企鹅出版社(Penguin Press)出版。英国《金融时报》的一篇书评称赞该书“非比寻常”。该书是在同终选名单中的另外五部作品展开激烈竞争后脱颖而出的。另五部作品尝试解决的是世界上一些重要的经济与管理难题——从美国的生产率缺口,到持续存在的性别失衡。
United States emissions had been declining because of increased burning of natural gas in power generation, which emits less carbon dioxide for each unit of energy than does coal. But the nation reported an increase in 2013 as coal regained some market share. If that trend continues, it could prove to be a challenge for the Obama administration as it seeks to institute tighter policies on greenhouse gases.
愿新年为你带来快乐,友爱和宁静。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Tech giant Tencent's founder Pony Ma topped the list, with a fortune of 279 billion yuan, followed by Alibaba's Jack Ma, and Evergrande Group's Xu Jiayin, with their personal worth reaching 260 billion yuan, and 229 billion yuan, respectively.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

除了这一综合排行榜,《美国新闻与世界报道》还提供了地区、国家、特定专业大学排行榜,方便大家进行更为细致的搜索。
Last year, the CPI increase peaked at 2.5 percent in January, and later fluctuated below 2 percent during the rest of the year.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Recipient: His Royal Highness Prince Harry

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

这位名叫波比·博伊登的小选美冠军穿着一身黑色的连衣裤,带着鬈曲的假发,非常熟练的跳着扭臀舞,向观众们飞吻。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

澳大利亚管理研究生院的一名毕业生表示:“最初,我对攻读在线课程颇有疑虑,但沟通和在线互动非常棒。”
华莱士对一切说“好”说了一年,然后写了这本书。这个尝试既促进了他的事业,也把他带进过邪教集会。不过,电影没说的是,华莱士曾在数不清的钓鱼网站注册。显然,一直说“好”在现实生活中可不是一帆风顺。
1995年,荷兰维和部队未能阻止波黑塞族军队在位于波黑东部的斯雷布雷尼察杀害8000名穆斯林男子和男孩。
两人的正式获奖词说的是表彰其“稳定匹配理论和市场设计实践”。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

单词facilitate 联想记忆:
Mr Baweja’s extensive analysis on the changing nature of globalisation suggests the prime factor behind the weakness of global trade growth (which for a long time expanded at twice the rate of global GDP) has been a slowdown in investment.
Seoul insists the activists have a democratic right to send the leaflets, but has appealed for restraint to avoid overly provoking the North.
The main culprit for the deceleration was food, though food inflation is higher than the overall index. Food prices were up 1.9 per cent in October, down from 2.7 per cent in September and 3.7 per cent in August. Non-food inflation ticked down 0.9 per cent from 1.0 per cent.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 放开海岛“买卖”,盘活海洋资源
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Mila Kunis just keeps on raking in those sexy titles.
Average age: 33 in Philadelphia, 36 in San Francisco

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

"We'll start with a broad list and then begin to narrow it," Podesta told the Boston Globe. "But there is no question that there will be women on that list."

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

5.Create a Study Space

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

上海社会科学院的专家周海旺告诉环球时报:“上海自2014以来就采取了一系列强硬措施,包括改造城中村和规范群租来控制人口增长。”
The second match will be held at the Mercedes-Benz Arena in Shanghai on Oct 8.
因此,看看吧。我真诚地希望你们会喜欢它们,就像我在挑选和编辑它们时那样。
Zhang Jingxiu, executive director of Beijing-based employment consultancy Newjincin Research Institute, said he didn't monitor the significant decrease of students' willingness to start businesses, but he does admit the desire to found startups among students on campus is low.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

A robust LinkedIn presence is crucial to any job search. You know that. Your manager knows that. And your manager probably knows that you know that – so she'll be concerned when you go from having a bare-bones profile on Monday to one jacked with additional work history, new connections, status updates and recommendations by Friday. "Don't go from zero to 500 overnight, because that can be quite obvious," Foss cautions。
Skin has the thankless job of coating and protecting your whole body, making it your most easily damaged organ. When you burn or rip off a stretch of skin, your main option right now is to graft some back on from elsewhere on your body. But an effective synthetic replacement skin may not be that far off, thanks to research from Stanford scientists.
This is the second year running that Peking University has reached the height of No. 2 university.
单词lasting 联想记忆:

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

在动画电影行业执迷于翻拍让观众有共鸣的老故事时,皮克斯却总能尝试新事物,把观众带到从未踏足的新领域。《寻梦环游记》由《玩具总动员3》导演李?昂克里奇执导,该片的视觉效果基于墨西哥的亡灵节。故事讲述了一个名叫米格尔的小男孩崇拜传奇吉他手欧内斯托?德?拉?克鲁兹,想学习如何能弹奏得和他一样好。于是他就像奥德赛一样踏上了改造性的自我发现之旅,进入死亡之地寻找那位已去世多年的偶像,还受到了一些关于创造力本质的教导。《寻梦环游记》是否能达到皮克斯2015年杰作《头脑特工队》的高度尚未可知,但这部电影绝对是一场视觉盛宴。该片将于11月15日在法国上映,11月22日在美国、克罗地亚和菲律宾上映,11月30日在以色列上映。(资料来源:迪士尼/皮克斯)
认为西方民主政体不会受影响将是愚蠢的。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

基地方面希望借此提升公众意识,宣扬保护区及熊猫保护的理念,同时在中国进行动物野生放归,增加中国部分物种濒危区的动物数量。
[l?un]
单词corporate 联想记忆:
A report from the ministry showed that employers recruited 5.2 million workers through public employment service agencies in the first quarter, dropping 229,000, or 4.5 percent, from the previous year.
The Big Bang Theory is not short on geniuses. Not only is the show about highly intelligent scientists, but cast member Mayim Bialik has a Ph.D. in Neuroscience. So it should come as no surprise that the cast would want to show off their intelligence and attention to detail. In Sheldon and Leonard's apartment, there's a large white board. The two roommates use the board frequently for everything from actual work that Leonard or Sheldon has brought home, or to decide whether to eat before or after the new Spider-Man movie.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

With the release of his book Conscious Capitalism, Whole Foods (WFM, Fortune 500) CEO John Mackey got business leaders thinking about a compelling idea: Companies work best when they create value for all their stakeholders -- not just investors. According to Mackey, key stakeholders include customers, employees, suppliers, society, and the environment. Highlighting companies like Costco, Southwest Airlines (LUV,Fortune 500), and Google (GOOG, Fortune 500), Mackey demonstrates that thinking about more than just the bottom line builds stronger and more efficient businesses.
37| “Anomalisa” (Charlie Kaufman/Duke Johnson)|
Tom Petty

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

“中国银行业面临的逆风将延续很长时间,”他说。“除了盈利来源减少,它们还将不得不为坏账带来的亏损做好准备。”
Currency movements have had a strong impact on agricultural commodity prices this year, with the UK’s referendum on the EU leading to a sharp fall in the pound that pushed up the price of food imports and boosted agricultural exports.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 新时代房企发展面临四维转型
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

vt. 买,购买
"He was not on the intelligence services' radar," added the prime minister.
The Baltic Dry index, a measure of the trade in bulk commodities, has been touching historic lows. China, which in 2014 overtook the US as the biggest trading nation, this month reported double-digit falls in both exports and imports in January. In Brazil, which is experiencing its worst recession in more than a century, imports from China have collapsed.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

polish
And in the UK, could this be the year that the big consultancies make proper inroads into the legal market Will other “alternative business structures” — aka purveyors of “Tesco law” — finally gain a toehold at the consumer end by offering fixed-fee services, putting work out to tender to loose networks of lawyers, or cranking up the legal chatbot for instant, affordable advice Someone has to bust this sector open for the sake of the average citizen.
Look no further than the title sponsor on their building—Smoothie King, a regional drink shop—to realize that the Pelicans have a serious relevancy problem. (By contrast, the NFL's Saints play in the Mercedes-Benz Superdome next door.)

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

如果此时打断老师讲课不太合适,你可以快速记下自己的问题,以免忘记,之后再问老师。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

本文为与《创业者》杂志的合作内容。下文最初发表于Entrepreneur.com。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

We must make dedicated efforts to deliver services to the people, resolve the difficulties they face, promote social equity and justice, and demonstrate that development does better people’s lives.
2017年排行榜分别评选了60个“无工作经验要求”的项目和6个“有工作经验要求”的项目。“无工作经验要求”的项目主要面向拥有很少或没有金融业背景的学生,“有工作经验要求”的项目针对的是已经在金融领域工作的专业人士。只有少数几家学院提供“有工作经验要求”的课程。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

专业一点
5.生物医学工程师
在英国,今年可能是大型咨询公司正式进入法律市场的一年吗?其他的“另类业务结构”——或者说按照“乐购法”(Tesco law)成立的律所——将通过提供固定费用服务、把业务外包给松散的律师网络,或者推出法律聊天机器人提供即时而实惠的建议,而终于立足消费者市场吗?为了普通公民的利益,得有人突破这个领域。
据外媒体育网站sbnation.com报道,德国战车在刚刚结束的比赛中以四粒进球完胜葡萄牙。比赛结果令人震惊,多数观察员原本希望葡萄牙的攻势能更猛烈些。但这是否是本届世界杯又一场比分悬殊的比赛?的确不足为奇。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

今年上榜的中国品牌有36个,其中8个进入前100名,包括国家电网(36)、中国工商银行(40)、腾讯(43)、央视(62)、海尔(76)、中国移动(79)、华为(81)和联想(90)。
Those concerns are casting a heavy shadow over a two-day meeting of G20 central bank governors and finance ministers due to start tomorrow. The International Monetary Fund this week already warned that it was poised to downgrade its forecast for global growth this year, saying the leading economies needed to do more to boost growth.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 辛识平:奋斗应提倡 996当退场
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

这些人工眼睛,确实恢复了盲鼠的视力。猴子的视网膜工作原理和人类的非常相似,因此随后在猴子上进行的试验给了最终的人类试验以成功的希望。
No one in Detroit has forgotten the snowstorm of 1999, when airplanes were mired for hours on the tarmac at Detroit Metropolitan International Airport. Likewise, US Airways encountered its own holiday mishap in 2004-05, when more than 72, 000 bags were lost or damaged.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

巴西对智利比赛的正式票价范围在200美元到25美元之间。最便宜的门票大约占5%的销售额。这些门票只为学生、老年人和政府福利计划的穷人提供。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 去年北京公积金个贷大增55.2%
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

In this Jan. 7, 1997, file photo, Steve Jobs, chief executive of Pixar, speaks at the MacWorld trade show in San Francisco.
清华大学和北京大学分别排在第14位和第17位,与它们去年各自的排名相同。
无从业资格的司机从事网约车服务将面临1万(折合1500美元)至3万元(折合4500美元)的罚款。
“The Diary of a Teenage Girl” (Marielle Heller)

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

单词infection 联想记忆:
4、Tardiness

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Days after her death, Ross’ mother, Alicia Jesquith, told reporters she needed answers for the sudden death of her daughter, described by friends and family as a vibrant, ambitious young girl who lit up the room.
单词ridiculous 联想记忆:
20. Best Advice for Movie Lovers In August, the scholar Wheeler Winston Dixon sounded an alarm: “If you go on Amazon and you see some great black-and-white film, and it’s going for $3, or any kind of foreign or obscure film, buy it, because it’s going out of print, and they’re not going to put them back into print.” Tens of thousands of films that were on VHS never made the jump to DVD or to Blu-ray, Mr. Dixon warns. And the brave new world of downloads (a.k.a. electronic sell-through) — well, tune in next year.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Release date: Spring 2015
单词stable 联想记忆:
事实是,韩力不是第一个发明电子烟的人。早在1963年,赫尔伯特·吉尔伯特就制造出了世界上第一个可以用来吸入香烟味儿空气的装置。他最初的发明装置,不用燃烧,也不含尼古丁。他后来设计出了一个用电池去加热的模型,他也用了不同味道的水去制造蒸气。他把他的电子烟模型展示给不同的化工、制药以及烟草公司,但是他们都没有理会他的模型。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Given the Raptors' existing personnel, the Ibaka/Tucker additions qualify as massive defensive upgrades, giving coach Dwane Casey the tools he will need to grind out postseason wins if Lowry and DeMar DeRozan see their scoring efficiency dip as it has in years past.
sen年老+ior表形容词,“较…的”→年长的

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 广西北海居住证办理“立等可取”
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 广州:毕业季租房多了租金涨了
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

in进入,stitute站,建立-站进去;进入建立的状态-创立
《自己土地上的陌生人: 美国右翼的愤怒与哀悼》(Strangers in Their Own Land: Anger and Mourning on the American Right)一书的作者阿莉?罗素?霍克希尔德(Arlie Russell Hochschild)对路易斯安那州的农村社区进行了四年的研究,她认为那里“深藏着”一种失去机会的感觉。
A fallen tree blocks a street in Washington, DC, on Tuesday.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

阿丽莎也微笑地说道:“无可挑剔,一直唱下去,男孩们!”
Men and women rated the strengths of their programme equally.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

[kri'eitiv]
立场:为禁止员工在家上班进行辩解
The reality turned out to be tougher than he imagined. “I saw it as a two-year opportunity,” says Mr Ravenscroft. “The grinding reality is that it’s a slog.” Moreover, his mentor worked at Lehman Brothers, the bank that collapsed in 2008. “It wasn’t quite as long a mentoring relationship as I’d hoped,” he laughs.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Caleb Rogers is one of two people facing legal action from gaming studio Epic Games for using cheat software to play the game Fortnite.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

多年来,人们一直预测这个分散的行业将会整合,近期的确出现了大规模合并。但毫无疑问,伦敦金融城的律师事务所正在承受越来越大的价格压力。
Among the 18 sectors categorized by the China Securities Regulatory Commission, financial executives ranked the highest with annual pay of 27.36 million yuan, followed by real estate executives at 11.18 million yuan.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

这些各不相同的胡子是设计师弗朗西丝·汉农(Frances Hannon)设计的,在安德森的多部电影中(比如《青春年少》[Rushmore]和《水中生活》[The Life Aquatic With Steve Zissou]),她都为比尔·默里(Bill Murray)设计了面部毛发。这次,她让该片的很多演员留起胡子,供她修剪成任何想要的形状。
Prior to the slowdown that began in 2014 employers in China had been less stingy with cash bonuses, which can total well over a full month’s salary and send employees back home for the holiday with plenty of cash for gifts to elders and other family members (or to squirrel away as savings).

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 2015年最新钢木门十大品牌排行榜
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

大部分的科技从业人员都认为移动应用会发展、而电脑应用会减弱。这意味着企业都需要强劲、快捷和实用的移动平台,不重视这点的企业必然会失去消费者。
vigor(n 精力;活力)

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

adj. 有益的,有利的
distract

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

立场:支持移民改革

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

去年,CPI指数上涨在一月时达到峰值2.5%,随后在剩下的时间里在2%以下波动。
Song “The China Style”(Jiuyue Qiji)
But pop's wider world also offered a lot of pleasures from artists all over the spectrum, such as the 20th century legends like Blondie and Tori Amos, and upstarts like Dua Lipa and Girl Ray.
Tencent, with an estimated value of $44.7 billion, was crowned this year's Most Valuable Chinese brand on a list released by the Hurun Institute on Thursday, marking the second time in a row it came up on top.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

The local court gave Zhou a lenient sentence due to the teenager's age and frank confession of the crime, according to the report.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

adj. 傲慢的,自大的
我只是忍不住希望,随着《广告狂人》的终结,一个时尚阶段也能终结,在这个阶段,设计师们被困于过去的时代,几乎窒息——至少是困在20世纪60年代(不要忘了,60年代初与50年代末非常相似)至70年代初。
鉴于标普500和纳斯达克指数都回升了14%以上,道琼斯和标普400中型股指数也都回升了近10%,你可能会认为今年被动投资者应该收获颇丰。确实,要不是那些恼人的海外股业绩不佳,大拖多元化投资组合的后腿,被动投资者原本应该值得庆祝。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The top 10 Weibo celebrities now have a combined 40 million followers. One of the most famous online figures, Papi Jiang, already signed a contract for video ads worth a staggering 22 million.
It can transport rows of seedlings in minutes. And can reduce planting time by 88 percent.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

'Nebraska' gets to the heart of Bruce Dern's prickly old geezer, Woody Grant, by way of a road trip across Montana and Nebraska, shot in radiant black-and-white. (Here again one of the movie's stars is its cinematographer, Phedon Papamichael.) Alexander Payne directed, flawlessly, from Bob Nelson's stellar script, which is all about thwarted love, and reconciliation, between Woody and his son Will; he's played with painfully quiet eloquence by Will Forte. Here's the American heartland as it's seldom portrayed on screen, with humor and almost palpable fondness.
Miranda Lambert “Bathroom Sink” (RCA Nashville)

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

1. Apple. Brand love: 57% / Rank: 32

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

It will be a year when the automaker begins selling its first airplane, the HA-420 Hondajet for general aviation, as well as a new hydrogen fuel-cell vehicle, the FCV. Honda will return to the Formula One circuit with a new race car. The cherry on top may be Acura NSX, a gas-electric hybrid supercar that will be built and sold in low volume.
BROAD CITY (Comedy Central, Jan. 14) Ilana Glazer and Abbi Jacobson return for a second season of satirizing the poses, compromises and sheer physical grossness of life in New York when you’re underemployed and self-absorbed.
自1983年以来,每年的央视春晚就成为了中国人民春节必不可少的重要组成部分,也难怪主办方的每个举动都能成为关注的焦点。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

中公教育表示,周二报名的岗位中最抢手的是位于北京的中国就业培训技术指导中心的职位,已有1430人报考了该职位。
节目19 歌曲《一辈子朋友》,杨坤 张靓颖
“Cooling measures [are] the most important issue affecting the [residential] property market in Hong Kong,” says Thomas Lam, head of valuation at Knight Frank. “That is why all the major institutional plans are looking at the office market in the past two or three years.”
For the students interested in comparing school options around the world, US News released the fourth edition of its annual Best Global Universities rankings.

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 愿奋斗者们住有所居,心有所属
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

As the stars' private jets swooped in, the internet was going mad for 'the Dad bod'; the slightly flabby male physique was trending and there were plenty of examples on screen. Deborah Cole of AFP noted a “sweating, panting and shirtless” Gerard Depardieu in Valley of Love and a flash of Joaquin Phoenix's “tubby tummy” in Woody Allen's Irrational Man. When Colin Farrell strode the red carpet for the premiere of The Lobster, he looked his usual trim self – but in the film he is distinctly paunchy. To add some girth for the role of a lonely singleton in Yorgos Lanthimos' absurdist black comedy, Farrell went on a massively calorific diet that included drinking melted ice cream, he told the Hollywood Reporter. Eating “two cheeseburgers, fries and Coca-Colas, and two slices of chocolate cake at 10am is not that fun,” he said. “And I love cheese?burgers."
Yes. Mr Meade is the candidate of the ruling Institutional Revolutionary Party, or PRI. His main rival is the hard leftist Andrés Manuel López Obrador, a passionate orator who can work a crowd. Mr Meade has a lot to overcome: he will have to convince voters that they can trust him, after he put up petrol prices by 20 per cent overnight in January, triggering a surge in inflation. He will also have to reveal himself as his own man, not just a clone of an unpopular government that has failed spectacularly to rein in rampant corruption and crime. But backed by the formidable PRI get-out-the-vote machine, he could prove unstoppable. In Mexico’s one-round-only system, 30 per cent of the vote might be enough.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

葡萄牙诺瓦商业与经济学院(Nova School of Business and Economics)巩固了去年的强劲表现,排名进一步攀升14个位置,排在了第17位。
这项研究需要对夫妻互动时的情绪进行庞大的纵向研究。
About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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“The steady and now record-breaking rise in average global temperatures is not an issue for another day,” Michael R. Bloomberg, the former New York mayor who is spending tens of millions of dollars of his personal fortune to battle climate change, said in a statement. “It’s a clear and present danger that poses major economic, health, environmental and geopolitical risks.”
10. A bad marriage can lead to an early death

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